Critical illness polyneuropathy, myopathy and neuronal biomarkers in COVID-19 patients: A prospective study.

ABSTRACT:

Objective

The aim was to characterize the electrophysiological features and plasma biomarkers of critical illness polyneuropathy (CIN) and myopathy (CIM) in coronavirus disease 2019 (COVID-19) patients with intensive care unit acquired weakness (ICUAW).

Methods

An observational ICU cohort study including adult patients admitted to the ICU at Uppsala University Hospital, Uppsala, Sweden, from March 13th to June 8th 2020. We compared the clinical, electrophysiological and plasma biomarker data between COVID-19 patients who developed CIN/CIM and those who did not. Electrophysiological characteristics were also compared between COVID-19 and non-COVID-19 ICU patients.

Results

111 COVID-19 patients were included, 11 of whom developed CIN/CIM. Patients with CIN/CIM had more

SUBMITTER: Frithiof R 

PROVIDER: S-EPMC8012169 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature