Carbon cloth-based immunosensor for detection of 25-hydroxy vitamin D₃.

ABSTRACT: Vitamin D (VD) deficiency is a global health concern due to its serious health impacts, and at present, the monitoring of VD status is expensive. Here, a novel immunosensor for sensitive and label-free detection of 25-hydroxy vitamin D₃ (25VD₃) is reported. Nanostructured cerium(IV) oxide (nCeO₂) was anchored onto carbon cloth (CC) via electrophoretic deposition to fabricate a nanoplatform (nCeO₂/CC). Subsequently, bioactive molecules (anti-25VD₃ and BSA) were introduced to fabricate the nanobioplatform BSA/anti-25VD₃/nCeO₂/CC as an immunosensor. The analytical performance of the developed immunosensor was studied towards 25VD₃ detection. The immunosensor provides a broad linear range of 1-200 ng mL

SUBMITTER: Chauhan D 

PROVIDER: S-EPMC8012417 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature