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Diethyl Malonate-Based Turn-On Chemical Probe for Detecting Hydrazine and Its Bio-Imaging and Environmental Applications With Large Stokes Shift.

ABSTRACT: Diethyl malonate-based fluorescent probe NE-N ₂ H ₄ was constructed for monitoring hydrazine (N₂H₄). The novel probe NE-N ₂ H ₄ exhibits good properties, such as large Stokes shift (about 125 nm), good selectivity, and low cytotoxicity. This sensing probe NE-N ₂ H ₄ can be operated to detect hydrazine in living HeLa cells. Especially after soaking in probe solution, the thin-layer chromatography (TLC) plate could detect the vapor of hydrazine. Therefore, the probe NE-N ₂ H ₄ might be used to monitor hydrazine in biosamples and environmental problem.

SUBMITTER: Qu J

PROVIDER: S-EPMC8012553 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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Diethyl Malonate-Based Turn-On Chemical Probe for Detecting Hydrazine and Its Bio-Imaging and Environmental Applications With Large Stokes Shift.

Qu Jianbo J Zhang Zhi-Hao ZH Zhang Haitao H Weng Zhen-Tao ZT Wang Jian-Yong JY

Frontiers in chemistry 20210318

Diethyl malonate-based fluorescent probe NE-N 2 H 4 was constructed for monitoring hydrazine (N2H4). The novel probe NE-N 2 H 4 exhibits good properties, such as large Stokes shift (about 125 nm), good selectivity, and low cytotoxicity. This sensing probe NE-N 2 H 4 can be operated to detect hydrazine in living HeLa cells. Esp ...[more]

PMID: 33816431

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