Effects of Simulated Microgravity on the Proteome and Secretome of the Polyextremotolerant Black Fungus <i>Knufia chersonesos</i>.

ABSTRACT: Black fungi are a group of melanotic microfungi characterized by remarkable polyextremotolerance. Due to a broad ecological plasticity and adaptations at the cellular level, it is predicted that they may survive in a variety of extreme environments, including harsh niches on Earth and Mars, and in outer space. However, the molecular mechanisms aiding survival, especially in space, are yet to be fully elucidated. Based on these premises, the rock-inhabiting black fungus Knufia chersonesos (Wt) and its non-melanized mutant (Mut) were exposed to simulated microgravity-one of the prevalent features characterizing space conditions-by growing the cultures in high-aspect-ratio vessels (HARVs). Qualitative and quantitative proteomic analyses were performed on the mycelia and supernatant of

SUBMITTER: Tesei D 

PROVIDER: S-EPMC8012687 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature