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Organoid biobanks as a new tool for pre-clinical validation of candidate drug efficacy and safety.


ABSTRACT: The growing need for personalized medicine for cancer patients has enhanced and optimized the production of living tumor organoids that have become optimal preclinical models for the discovery and screening of anticancer drugs. The systematic collection and storage of tumor organoids through the establishment of dedicated biobanks will represent a fundamental tool for cancer research and clinical trials.

SUBMITTER: Botti G 

PROVIDER: S-EPMC8012858 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature

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Organoid biobanks as a new tool for pre-clinical validation of candidate drug efficacy and safety.

Botti Gerardo G   Di Bonito Maurizio M   Cantile Monica M  

International journal of physiology, pathophysiology and pharmacology 20210215 1


The growing need for personalized medicine for cancer patients has enhanced and optimized the production of living tumor organoids that have become optimal preclinical models for the discovery and screening of anticancer drugs. The systematic collection and storage of tumor organoids through the establishment of dedicated biobanks will represent a fundamental tool for cancer research and clinical trials. ...[more]

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