Usefulness of quantitative susceptibility mapping for the diagnosis of Parkinson disease.

ABSTRACT:

Background and purpose

Quantitative susceptibility mapping allows overcoming several nonlocal restrictions of susceptibility-weighted and phase imaging and enables quantification of magnetic susceptibility. We compared the diagnostic accuracy of quantitative susceptibility mapping and R2* (1/T2*) mapping to discriminate between patients with Parkinson disease and controls.

Materials and methods

For 21 patients with Parkinson disease and 21 age- and sex-matched controls, 2 radiologists measured the quantitative susceptibility mapping values and R2* values in 6 brain structures (the thalamus, putamen, caudate nucleus, pallidum, substantia nigra, and red nucleus).

Results

The quantitative susceptibility mapping values and R2* values of the substantia nigra were significa

SUBMITTER: Murakami Y 

PROVIDER: S-EPMC8013031 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature