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Estimation of undetected symptomatic and asymptomatic cases of COVID-19 infection and prediction of its spread in the USA.


ABSTRACT: The reported COVID-19 cases in the United States of America have crossed over 10 million and a large number of infected cases are undetected whose estimation can be done if country-wide antibody testing is performed. In this study, we estimate this undetected fraction of the population by a modeling and simulation approach. We employ an epidemic model SIPHERD in which three categories of infection carriers, symptomatic, purely asymptomatic, and exposed are considered with different transmission rates that are taken dependent on the social distancing conditions, and the detection rate of the infected carriers is taken dependent on the tests done per day. The model is first validated for Germany and South Korea and then applied for prediction of the total number of confirmed, active and dead

SUBMITTER: Mahajan A 

PROVIDER: S-EPMC8013178 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature