CD169 and CD64 could help differentiate bacterial from CoVID-19 or other viral infections in the Emergency Department.

ABSTRACT: The identification of a bacterial, viral, or even noninfectious cause is essential in the management of febrile syndrome in the emergency department (ED), especially in epidemic contexts such as flu or CoVID-19. The aim was to assess discriminative performances of two biomarkers, CD64 on neutrophils (nCD64) and CD169 on monocytes (mCD169), using a new flow cytometry procedure, in patients presenting with fever to the ED during epidemics. Eighty five adult patients presenting with potential infection were included during the 2019 flu season in the ED of La Timone Hospital. They were divided into four diagnostic outcomes according to their clinical records: no-infection, bacterial infection, viral infection and co-infection. Seventy six patients with confirmed SARS-CoV-2 infection were also

SUBMITTER: Bourgoin P 

PROVIDER: S-EPMC8014466 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature