Obesity and Critical Illness in COVID-19: Respiratory Pathophysiology.

ABSTRACT:

Objective

Recent cohort studies have identified obesity as a risk factor for poor outcomes in coronavirus disease 2019 (COVID-19). To further explore the relationship between obesity and critical illness in COVID-19, the association of BMI with baseline demographic and intensive care unit (ICU) parameters, laboratory values, and outcomes in a critically ill patient cohort was examined.

Methods

In this retrospective study, the first 277 consecutive patients admitted to Massachusetts General Hospital ICUs with laboratory-confirmed COVID-19 were examined. BMI class, initial ICU laboratory values, physiologic characteristics including gas exchange and ventilatory mechanics, and ICU interventions as clinically available were measured. Mortality, length of ICU admission, and durat

SUBMITTER: Wolf M 

PROVIDER: S-EPMC8014725 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature