Synthesis of Curcumin Nanoparticles from Raw Turmeric Rhizome.

ABSTRACT: Turmeric (Curcuma longa L.) has been used as a spice and a medicinal herb since ancient times. The main active ingredient of turmeric is curcumin, a polyphenol that helps prevent and control neurological, respiratory, cardiovascular, metabolic, inflammatory, and autoimmune diseases and some cancers. However, curcumin has drawbacks such as low water-solubility, poor absorption, fast metabolism, quick systemic elimination, low bioavailability, poor pharmacokinetics, low stability, and low penetration targeting efficacy. To overcome these drawbacks, a common method used is encapsulating curcumin in nanocarriers for targeted delivery. However, the degraded products of nanocarriers have raised concerns. In this research, we synthesized nanoparticles of curcumin, nanocurcumin without usin

SUBMITTER: Hettiarachchi SS 

PROVIDER: S-EPMC8015141 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature