Serum vaspin levels are positively associated with diabetic retinopathy in patients with type 2 diabetes mellitus.

ABSTRACT:

Aims/introduction

Vaspin is linked to obesity and its metabolic abnormalities. However, the role of vaspin serum levels in diabetic retinopathy (DR) is unknown. In the present study, we investigated the association between serum levels of vaspin and both DR and vision-threatening DR.

Materials and methods

This was a cross-sectional single-center observational study from December 2018 to September 2019. We evaluated circulating serum levels of vaspin in 372 participants with type 2 diabetes. DR was screened through detailed ocular examination. DR patients were also divided two groups: vision-threatening DR and non-vision-threatening DR. The relationship between vaspin and DR was investigated by univariate and multivariate logistic regression analyses, and the results are show

SUBMITTER: Yang HW 

PROVIDER: S-EPMC8015830 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature