AT-CuAAC Synthesis of Mechanically Interlocked Oligonucleotides.

ABSTRACT: We present a simple strategy for the synthesis of main chain oligonucleotide rotaxanes with precise control over the position of the macrocycle. The novel DNA-based rotaxanes were analyzed to assess the effect of the mechanical bond on their properties.

SUBMITTER: Acevedo-Jake A 

PROVIDER: S-EPMC8016193 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature