Trends in US pediatric mental health clinical trials: An analysis of ClinicalTrials.gov from 2007-2018.

ABSTRACT: Whereas time trends in the epidemiologic burden of US pediatric mental health disorders are well described, little is known about trends in how these disorders are studied through clinical research. We identified how funding source, disorders studied, treatments studied, and trial design changed over the past decade in US pediatric mental health clinical trials. We identified all US pediatric interventional mental health trials submitted to ClinicalTrials.gov between October 1, 2007 and April 30, 2018 (n = 1,019) and manually characterized disorders and treatments studied. We assessed trial growth and design characteristics by funding source, treatments, and disorders. US pediatric mental health trials grew over the past decade (compound annual growth rate [CAGR] 4.1%). The number of studi

SUBMITTER: Wortzel JR 

PROVIDER: S-EPMC8016324 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature