Association of Neural Reward Circuitry Function With Response to Psychotherapy in Youths With Anxiety Disorders.

ABSTRACT:

Objective

Identifying neural correlates of response to psychological treatment may inform targets for interventions designed to treat psychiatric disorders. This study examined the extent to which baseline functioning in reward circuitry is associated with response to psychotherapy in youths with anxiety disorders.

Methods

A randomized clinical trial of cognitive-behavioral therapy compared with supportive therapy was conducted in youths with anxiety disorders. Before treatment, 72 youths (9-14 years old) with anxiety disorders and 37 group-matched healthy comparison youths completed a monetary reward functional MRI task. Treatment response was defined categorically as at least a 35% reduction in diagnostician-rated anxiety severity from pre- to posttreatment assessment. Pre

SUBMITTER: Sequeira SL 

PROVIDER: S-EPMC8016705 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature