Neuroimaging of depression with diffuse optical tomography during repetitive transcranial magnetic stimulation.

ABSTRACT: Repetitive transcranial magnetic stimulation (rTMS) is an effective and safe treatment for depression; however, its potential has likely been hindered due to non-optimized targeting, unclear ideal stimulation parameters, and lack of information regarding how the brain is physiologically responding during and after stimulation. While neuroimaging is ideal for obtaining such critical information, existing modalities have been limited due to poor resolutions, along with significant noise interference from the electromagnetic spectrum. In this study, we used a novel diffuse optical tomography (DOT) device in order to advance our understanding of the neurophysiological effects of rTMS in depression. Healthy and depressed subjects aged 18-70 were recruited. Treatment parameters were standardized

SUBMITTER: Jiang S 

PROVIDER: S-EPMC8016845 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature