Apigenin role as cell-signaling pathways modulator: implications in cancer prevention and treatment.

ABSTRACT: Cancer is a complex disease orchestrated by various extrinsic and intrinsic pathways. In recent years, there has been a keen interest towards the development of natural extracts-based cancer therapeutics with minimum adverse effects. In pursuit of effective strategy, a wide variety of natural products-derived compounds have been addressed for their anticancer effects. Apigenin is a naturally-occurring flavonoid present abundantly in various fruits and vegetables. Decades of research have delineated the pharmacological and biological properties of apigenin. Specifically, the apigenin-mediated anticancer activities have been documented in various types of cancer, but the generalized scientific evidence encompassing various molecular interactions and processes, such as regulation of the apopt

SUBMITTER: Javed Z 

PROVIDER: S-EPMC8017783 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature