Monitoring of COVID-19-Associated Coagulopathy and Anticoagulation with Thromboelastometry.

ABSTRACT:

Introduction

Thrombosis occurs frequently in COVID-19. While the exact mechanism is unclear, 3 processes seem to play important roles in sepsis-related thrombosis and mortality: tissue factor expression on circulating monocytes and microparticles, hypercoagulability (increased clot firmness), and hypofibrinolysis. Rotational thromboelastometry is a point-of-care viscoelastic technique that uses the viscoelastic properties of blood to monitor coagulation. Using various assays, viscoelastometry could monitor this triad of changes in severely ill, COVID-19-positive patients. Similarly, with the increased incidence of coagulopathy, many patients are placed on anticoagulants, making management more difficult depending on the agents utilized. Viscoelastometry might also be used in these

SUBMITTER: Katz D 

PROVIDER: S-EPMC8018202 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature