Evaluation of methods to derive blood flow velocity from 1000 fps high-speed angiographic sequences (HSA) using optical flow (OF) and computational fluid dynamics (CFD).

ABSTRACT: Digital Subtraction Angiography (DSA) is considered the gold standard for imaging and guiding treatment of neurovascular lesions, such as cerebral aneurysms and carotid stenoses. Though DSA can show high-resolution morphology, it remains difficult to extract temporal physiological information, because higher frame-rates are necessary to accurately quantify neurovascular flow details. Recent advances in photon-counting detector technology have led us to develop High-Speed Angiography (HSA), where X-ray images are acquired at 1000 fps for more accurate visualization and quantification of blood flow. Blood flow was imaged using HSA under constant flow conditions within various 3D printed patient-specific phantoms. Blood velocity was quantified using an open source Optical Flow algorithm, Open

SUBMITTER: Shields A 

PROVIDER: S-EPMC8018699 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature