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Interactive tool to create adjustable anatomical atlases for mouse brain imaging.


ABSTRACT:

Objective

Brain atlases are important research tools enabling researchers to focus their investigations on specific anatomically defined brain regions and are used in many MRI applications, e.g. in fMRI, morphometry, whole brain spectroscopy, et cetera. Despite their extensive use and numerous versions they usually consist of predefined rigid brain regions with a given level of detail often degrading them to a non-ideal tool in special research topics.

Result

To overcome this intrinsic weakness we present a graphical user interface application which allows researchers to easily create mouse brain atlases with an adjustable user-defined level of detail and coverage to match specific research questions.

SUBMITTER: Sack M 

PROVIDER: S-EPMC8018930 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature

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Interactive tool to create adjustable anatomical atlases for mouse brain imaging.

Sack Markus M   Zheng Lei L   Gass Natalia N   Ende Gabriele G   Sartorius Alexander A   Weber-Fahr Wolfgang W  

Magma (New York, N.Y.) 20200721 2


<h4>Objective</h4>Brain atlases are important research tools enabling researchers to focus their investigations on specific anatomically defined brain regions and are used in many MRI applications, e.g. in fMRI, morphometry, whole brain spectroscopy, et cetera. Despite their extensive use and numerous versions they usually consist of predefined rigid brain regions with a given level of detail often degrading them to a non-ideal tool in special research topics.<h4>Result</h4>To overcome this intr  ...[more]

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