Detection of loci exhibiting pleiotropic effects on body weight and egg number in female broilers.

ABSTRACT: The objective of the present study was to discover the genetic variants, functional candidate genes, biological processes and molecular functions underlying the negative genetic correlation observed between body weight (BW) and egg number (EN) traits in female broilers. To this end, first a bivariate genome-wide association and second stepwise conditional-joint analyses were performed using 2586 female broilers and 240 k autosomal SNPs. The aforementioned analyses resulted in a total number of 49 independent cross-phenotype (CP) significant SNPs with 35 independent markers showing antagonistic action i.e., positive effects on one trait and negative effects on the other trait. A number of 33 independent CP SNPs were located within 26 and 14 protein coding and long non-coding RNA genes, resp

SUBMITTER: Tarsani E 

PROVIDER: S-EPMC8018976 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature