Alterations in heart rate variability are associated with abnormal myocardial perfusion.

ABSTRACT:

Background

Abnormalities in the autonomic nervous system may occur in ischemic heart disease, but the mechanisms by which they are linked are not fully defined. The risk of cardiac events is increased during morning hours. Studying the contributions of autonomic mechanisms may yield insights into risk stratification and treatment. We hypothesize that autonomic dysfunction, measured by decreased heart rate variability (HRV), associates with abnormal stress myocardial perfusion imaging (MPI).

Methods

We performed a cross-sectional study of the association between abnormal myocardial stress perfusion with HRV using 276 middle-aged veteran twins without known ischemic heart disease. The primary independent variable was cardiac autonomic regulation measured with 24-hour electroca

SUBMITTER: Shah AS 

PROVIDER: S-EPMC8019069 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature