Functional adaptation of interradicular alveolar bone to reduced chewing loads on dentoalveolar joints in rats.

ABSTRACT:

Objectives

The effects of reduced chewing loads on load bearing integrity of interradicular bone (IB) within dentoalveolar joints (DAJ) in rats were investigated.

Methods

Four-week-old Sprague Dawley rats (N = 60) were divided into two groups; rats were either fed normal food, which is hard-pellet food (HF) (N = 30), or soft-powdered chow (SF) (N = 30). Biomechanical testing of intact DAJs and mapping of the resulting mechanical strains within IBs from 8- through 24-week-old rats fed HF or SF were performed. Tension- and compression-based mechanical strain profiles were mapped by correlating digital volumes of IBs at no load with the same IBs under load. Heterogeneity within IB was identified by mapping cement lines and TRAP-positive multinucleated cells using histology, and

SUBMITTER: Jang A 

PROVIDER: S-EPMC8019359 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature