Stereotactic MRI-guided laser interstitial thermal therapy for extratemporal lobe epilepsy.

ABSTRACT:

Objective

Magnetic resonance imaging (MRI)-guided laser interstitial thermal therapy (MRg-LITT) is an alternative to open epilepsy surgery. We assess safety and effectiveness of MRg-LITT for extratemporal lobe epilepsy (ETLE) in patients who are considered less favorable for open resection.

Methods

We retrospectively reviewed sequential cases of patients with focal ETLE who underwent MRg-LITT between 2012 and 2019. Epileptogenic zones were determined from standard clinical and imaging data ± stereoelectroencephalography (SEEG). Standard stereotactic techniques, MRI thermometry, and a commercial laser thermal therapy system were used for ablations. Anatomic MRI was used to calculate ablation volumes. Clinical outcomes were determined longitudinally.

Results

Thirty-five

SUBMITTER: Gupta K 

PROVIDER: S-EPMC8019400 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature