Morphological Characterization of small, dumpy, and long Phenotypes in Caenorhabditis elegans.

ABSTRACT: The determinant factors of an organism's size during animal development have been explored from various angles but remain partially understood. In Caenorhabditis elegans, many genes affecting cuticle structure, cell growth, and proliferation have been identified to regulate the worm's overall morphology, including body size. While various mutations in those genes directly result in changes in the morphological phenotypes, there is still a need for established, clear, and distinct standards to determine the apparent abnormality in a worm's size and shape. In this study, we measured the body length, body width, terminal bulb length, and head size of mutant worms with reported Dumpy (Dpy), Small (Sma) or Long (Lon) phenotypes by plotting and comparing their respective ratios of various

SUBMITTER: Cho JY 

PROVIDER: S-EPMC8019597 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature