The role of gastrointestinal pathogens in inflammatory bowel disease: a systematic review.
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ABSTRACT:
SUBMITTER: Axelrad JE
PROVIDER: S-EPMC8020742 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Publications
The role of gastrointestinal pathogens in inflammatory bowel disease: a systematic review.
Axelrad Jordan E JE Cadwell Ken H KH Colombel Jean-Frederic JF Shah Shailja C SC
Therapeutic advances in gastroenterology 20210331
The inflammatory bowel diseases (IBD), comprising Crohn's disease (CD) and ulcerative colitis (UC), are chronic, progressive, inflammatory conditions of the gastrointestinal tract. Imbalance in the gut microbial community, or dysbiosis, and the subsequent immune response, represent the critical relationship between genetic susceptibility, microbes, and environment factors, that result in IBD. Gastrointestinal pathogens - a common cause of dysbiosis - have been implicated as an environmental trig ...[more]
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