Transcriptional profile in rat muscle: down-regulation networks in acute strenuous exercise.

ABSTRACT:

Background

Physical exercise is a health promotion factor regulating gene expression and causing changes in phenotype, varying according to exercise type and intensity. Acute strenuous exercise in sedentary individuals appears to induce different transcriptional networks in response to stress caused by exercise. The objective of this research was to investigate the transcriptional profile of strenuous experimental exercise.

Methodology

RNA-Seq was performed with Rattus norvegicus soleus muscle, submitted to strenuous physical exercise on a treadmill with an initial velocity of 0.5 km/h and increments of 0.2 km/h at every 3 min until animal exhaustion. Twenty four hours post-physical exercise, RNA-seq protocols were performed with coverage of 30 million reads per sampl

SUBMITTER: Felipe SMDS 

PROVIDER: S-EPMC8020866 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature