Preparation of Enantioenriched Alkylcarbastannatranes via Nucleophilic Inversion of Alkyl Mesylates for Use in Stereospecific Cross-Coupling Reactions.

ABSTRACT: We report the preparation of enantioenriched secondary alkylcarbastannatranes via a stereoinvertive S_N2 reaction of enantioenriched alkyl mesylates and carbastannatranyl anion equivalents. Using this process, enantioenriched secondary alcohols may be converted into highly enantioenriched alkylcarbastannatranes, which are useful in stereospecific cross-coupling reactions.

SUBMITTER: Ralph G 

PROVIDER: S-EPMC8021098 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature