Mortality and associated risk factors in patients with blood culture positive sepsis and acute kidney injury requiring continuous renal replacement therapy-A retrospective study.

ABSTRACT:

Objectives

Septic acute kidney injury (AKI) requiring continuous renal replacement therapy (CRRT) carries a mortality risk nearing 50%. Risk factors associated with mortality in AKI patients undergoing CRRT with blood culture positive sepsis remain unclear as sepsis has been defined according to consensus criteria in previous studies.

Methods

Risk factors associated with intensive care unit (ICU), 90-day and overall mortality were studied in a retrospective cohort of 126 patients with blood culture positive sepsis and coincident severe AKI requiring CRRT. Comprehensive laboratory and clinical data were gathered at ICU admission and CRRT initiation.

Results

38 different causative pathogens for sepsis and associated AKI were identified. ICU mortality was 30%, 90-day mor

SUBMITTER: Jarvisalo MJ 

PROVIDER: S-EPMC8021149 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature