Arsenic, blood pressure, and hypertension in the Strong Heart Family Study.

ABSTRACT:

Background

Arsenic has been associated with hypertension, though it is unclear whether associations persist at the exposure concentrations (e.g. <100 μg/L) in drinking water occurring in parts of the Western United States.

Methods

We assessed associations between arsenic biomarkers and systolic blood pressure (SBP), diastolic blood pressure (DBP), and hypertension in the Strong Heart Family Study, a family-based cohort of American Indians from the Northern plains, Southern plains, and Southwest. We included 1910 participants from three study centers with complete baseline visit data (2001-2003) in the cross-sectional analysis of all three outcomes, and 1453 participants in the prospective analysis of incident hypertension (follow-up 2006-2009). We used generalized estimating

SUBMITTER: Kaufman JA 

PROVIDER: S-EPMC8021390 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature