Association between Second-hand Smoke Exposure and Urinary NNAL Level in Korean Adolescents.

ABSTRACT:

Background

The 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) is a metabolite of tobacco-specific lung carcinogen that can be found in both smokers and non-smokers. Particularly, NNAL levels of children with a history of exposure to second-hand smoke (SHS) are higher than those of adults. Thus, we aimed to investigate the association between SHS exposure and urine NNAL levels in Korean adolescents.

Methods

This cross-sectional study used data from the Korea National Health and Nutrition Examination Survey VII. Overall, 648 never-smoking adolescents (425 boys and 223 girls) aged 12 to 18 were included in this study. Logistic regression analyses identified the relationship between SHS exposure and elevated urine NNAL levels.

Results

The mean urine NNAL levels of t

SUBMITTER: You HS 

PROVIDER: S-EPMC8021977 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature