Association of Preterm Birth With Long-term Risk of Heart Failure Into Adulthood.

ABSTRACT:

Importance

Preterm birth has been associated with increased risk of heart failure (HF) early in life, but its association with new-onset HF in adulthood appears to be unknown.

Objective

To determine whether preterm birth is associated with increased risk of HF from childhood into mid-adulthood in a large population-based cohort.

Design, setting, and participants

This national cohort study was conducted in Sweden with data from 1973 through 2015. All singleton live births in Sweden during 1973 through 2014 were included.

Exposures

Gestational age at birth, identified from nationwide birth records.

Main outcomes and measures

Heart failure, as identified from inpatient and outpatient diagnoses through 2015. Cox regression was used to determine hazard ratios

SUBMITTER: Crump C 

PROVIDER: S-EPMC8022265 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature