Straightforward Access to Thiocyanates via Dealkylative Cyanation of Sulfoxides.

ABSTRACT: Thiocyanates, versatile building blocks in organic synthesis, are shown to be easily accessible via an interrupted Pummerer reaction of sulfoxides. This facile dealkylative functionalization proceeds under mild conditions through electrophilic activation of the sulfoxide partner. The resulting thiocyanate itself can serve as a handle for diversification in a straightforward one-pot procedure.

SUBMITTER: Todorovic U 

PROVIDER: S-EPMC8022320 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature