Intradialytic hypotension and relationship with cognitive function and brain morphometry.

ABSTRACT:

Background

The haemodynamic stress brought about by dialysis could justify the loss of structural and functional integrity of the central nervous system (CNS). The main objective of this study was to analyse the relationship between intradialytic hypotension (IDH) and cognitive function and brain morphometry.

Methods

The cross-sectional KIDBRAIN study (Cohort Study of Morphological Changes of the Brain by MRI in Chronic Kidney Disease Patients) included 68 prevalent patients with no history of neurological disorders (cerebrovascular disease and cognitive impairment) undergoing haemodialysis (HD). We analysed 18 non-consecutive dialysis sessions (first three of each month over a 6-month period) and various definitions of IDH were recorded. Global cognitive function (GCF) was

SUBMITTER: Cedeno S 

PROVIDER: S-EPMC8023187 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature