The Association of Antibiotic Duration With Successful Treatment of Community-Acquired Pneumonia in Children.

ABSTRACT:

Background

National guidelines recommend 10 days of antibiotics for children with community-acquired pneumonia (CAP), acknowledging that the outcomes of children hospitalized with CAP who receive shorter durations of therapy have not been evaluated.

Methods

We conducted a comparative effectiveness study of children aged ≥6 months hospitalized at The Johns Hopkins Hospital who received short-course (5-7 days) vs prolonged-course (8-14 days) antibiotic therapy for uncomplicated CAP between 2012 and 2018 using an inverse probability of treatment weighted propensity score analysis. Inclusion was limited to children with clinical and radiographic criteria consistent with CAP, as adjudicated by 2 infectious diseases physicians. Children with tracheostomies; healthcare-associated,

SUBMITTER: Same RG 

PROVIDER: S-EPMC8023315 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature