Aflatoxin exposure and child nutrition: measuring anthropometric and long-bone growth over time in Nepal.

ABSTRACT:

Background

Naturally occurring aflatoxins may contribute to poor growth and nutritional statuses in children.

Objectives

We analyzed the relationship between contemporary and lagged aflatoxin exposure and 1) length-for-age z-score (LAZ); and 2) length, knee-heel length, stunting, weight-for-age z-score (WAZ), and weight-for-length z-score (WLZ).

Methods

We conducted a longitudinal birth cohort study involving 1675 mother-infant dyads in rural Nepal. Participants were repeatedly visited from pregnancy to 2 years of age (2015-2019). One blood sample was collected during pregnancy and 4 samples were collected from the children at 3, 6, 12, and 18-22 months of age to measure concentrations of aflatoxin B1 (AFB1)-lysine adduct. Multivariate linear fixed-effects and logisti

SUBMITTER: Andrews-Trevino JY 

PROVIDER: S-EPMC8023848 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature