Point-of-care detection of lactate in cerebrospinal fluid.

ABSTRACT:

Purpose

Measurements of cerebrospinal fluid (CSF) lactate can aid in detecting infections of the central nervous system and surrounding structures. Neurosurgical patients with temporary lumbar or ventricular CSF drainage harbor an increased risk for developing infections of the central nervous system, which require immediate therapeutic responses. Since blood gas analyzers enable rapid blood-lactate measurements, we were interested in finding out if we can reliably measure CSF-lactate by this point-of-care technique.

Methods

Neurosurgical patients on our intensive care unit (ICU) with either lumbar or external ventricular drainage due to a variety of reasons were included in this prospective observational study. Standard of care included measurements of leucocyte counts, tot

SUBMITTER: Stephani C 

PROVIDER: S-EPMC8024429 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature