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Feasibility of intraoperative diagnosis of lung adenocarcinoma in situ to avoid excessive resection.


ABSTRACT:

Background

Limited lung resection is generally believed to be available for lung adenocarcinoma in situ (AIS). At our institute, intraoperative hematoxylin-eosin staining of frozen-section slides is routinely performed for evaluating tumor invasiveness after partial resection to avoid excessive lung resection. This study aimed to evaluate the feasibility and usefulness of intraoperative frozen-section diagnosis of AIS.

Methods

We retrospectively reviewed 143 patients with 151 AISs diagnosed by intraoperative frozen sections between 2012 and 2019 at our institute. All patients underwent limited resection because of the result of intraoperative frozen-section diagnosis.

Results

The total concordance rate between the diagnoses of AIS by intraoperative frozen sections and

SUBMITTER: Shima T 

PROVIDER: S-EPMC8024823 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature