Archaeogenomic distinctiveness of the Isthmo-Colombian area.

ABSTRACT: The recently enriched genomic history of Indigenous groups in the Americas is still meager concerning continental Central America. Here, we report ten pre-Hispanic (plus two early colonial) genomes and 84 genome-wide profiles from seven groups presently living in Panama. Our analyses reveal that pre-Hispanic demographic events contributed to the extensive genetic structure currently seen in the area, which is also characterized by a distinctive Isthmo-Colombian Indigenous component. This component drives these populations on a specific variability axis and derives from the local admixture of different ancestries of northern North American origin(s). Two of these ancestries were differentially associated to Pleistocene Indigenous groups that also moved into South America, leaving heterogeno

SUBMITTER: Capodiferro MR 

PROVIDER: S-EPMC8024902 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature