Effect of genome composition and codon bias on infectious bronchitis virus evolution and adaptation to target tissues.

ABSTRACT:

Background

Infectious bronchitis virus (IBV) is one of the most relevant viruses affecting the poultry industry, and several studies have investigated the factors involved in its biological cycle and evolution. However, very few of those studies focused on the effect of genome composition and the codon bias of different IBV proteins, despite the remarkable increase in available complete genomes. In the present study, all IBV complete genomes were downloaded (n = 383), and several statistics representative of genome composition and codon bias were calculated for each protein-coding sequence, including but not limited to, the nucleotide odds ratio, relative synonymous codon usage and effective number of codons. Additionally, viral codon usage was compared to host codon usage based on

SUBMITTER: Franzo G 

PROVIDER: S-EPMC8025453 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature