Shelter cats host infections with multiple Trypanosoma cruzi discrete typing units in southern Louisiana.

ABSTRACT: Trypanosoma cruzi is a zoonotic parasite endemic in the southern US and the Americas, which may frequently infect dogs, but limited information is available about infections in cats. We surveyed a convenience sample of 284 shelter cats from Southern Louisiana to evaluate T. cruzi infection using serological and PCR tests. Parasites from PCR positive cats were also genotyped by PCR and deep sequencing to assess their genetic diversity. We detected a seropositivity rate for T. cruzi of at least 7.3% (17/234), and 24.6% of cats (70/284) were PCR positive for the parasite. Seropositivity increased with cat age (R² = 0.91, P = 0.011), corresponding to an incidence of 7.2% ± 1.3 per year, while PCR positivity decreased with age (R² = 0.93, P = 0.007). Cats were predominantl

SUBMITTER: Dumonteil E 

PROVIDER: S-EPMC8025558 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature