Sequential haematological and serum biochemical changes in Black Bengal goats infected with a local isolate of peste des petits ruminants virus from Bangladesh.

ABSTRACT:

Background

Knowledge of sequential changes in haematobiochemical parameters of infected animals helps in the formulation of appropriate supportive therapy.

Objective

We investigated the sequential haematological and biochemical changes in peste des petits ruminants (PPR)-infected Black Bengal goats.

Methods

Goats were either infected with PPR virus (PPRV; n = 8) or sham infected with sterile phosphate-buffered saline (n = 4) via the intranasal route. Blood and sera were collected from both groups at different days post-infection (dpi) and analysed. Goats were sacrificed at different dpi and the amount of PPRV RNA in different tissues was quantified by real-time RT-PCR.

Results

The PPRV-infected goats showed mild depression and scanty nasal secretions starting a

SUBMITTER: Begum S 

PROVIDER: S-EPMC8025617 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature