The Survival Benefits of Surgical Resection and Adjuvant Therapy for Patients With Brainstem Glioma.

ABSTRACT:

Purpose

The role of surgical resection in the treatment of brainstem glioma (BSG) is poorly understood. For pediatric low-grade (LGBSG) group, several monocentric small-scale retrospective studies reported contradictory conclusions. And there was no clinical study focused on surgical resection for adult or pediatric high-grade (HG) patient groups. This study aims to illustrate whether surgical resection and adjuvant therapy provide survival benefits for patients with histologically confirmed BSG.

Patients and methods

This retrospective cohort study included 529 patients with histologically confirmed BSG in Surveillance Epidemiology and End Results (SEER) database from 2006-2015. Patients were divided into four groups by age and World Health Organization (WHO) grade. Kaplan-M

SUBMITTER: Liu Z 

PROVIDER: S-EPMC8027112 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature