Genomic Analysis of <i>Staphylococcus aureus</i> of the Lineage CC130, Including <i>mecC</i>-Carrying MRSA and MSSA Isolates Recovered of Animal, Human, and Environmental Origins.

ABSTRACT: Most methicillin resistant Staphylococcus aureus (MRSA) isolates harboring mecC gene belong to clonal complex CC130. This lineage has traditionally been regarded as animal-associated as it lacks the human specific immune evasion cluster (IEC), and has been recovered from a broad range of animal hosts. Nevertheless, sporadic mecC-MRSA human infections have been reported, with evidence of zoonotic transmission in some cases. The objective of this study was to investigate the whole-genome sequences of 18 S. aureus CC130 isolates [13 methicillin-resistant (mecC-MRSA) and five methicillin-susceptible (MSSA)] from different sequences types, obtained from a variety of host species and origins (human, livestock, wild birds and mammals, and water), and from differ

SUBMITTER: Gomez P 

PROVIDER: S-EPMC8027229 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature