Retrospective study of malignant phyllodes tumors of the breast: Younger age, prior fibroadenoma surgery, malignant heterologous elements and surgical margins may predict recurrence.

ABSTRACT:

Purpose

The potential recurrence rate of malignant phyllodes tumors (MPTs) of the breast is high, and the prognostic factors are still unclear. We therefore aim to study the factors affecting the outcome of MPTs.

Methods

A retrospective review of MPT patients treated from 2006 to 2020 at our institution was conducted. Univariate and multivariate Cox proportional hazard models were used to examine the influence of different variables on RFS. Moreover, significant prognostic factors were combined to construct the nomogram to predict the probability of relapse occurring in MPT patients. The 5-year and 10-year RFS rates were estimated using the Kaplan-Meier method.

Results

During the study period, 188 MPT patients were identified. The presence of malignant heterologous el

SUBMITTER: Li Y 

PROVIDER: S-EPMC8027899 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature