Effects of SlowMo, a Blended Digital Therapy Targeting Reasoning, on Paranoia Among People With Psychosis: A Randomized Clinical Trial.

ABSTRACT:

Importance

Persistent paranoia is common among patients with psychosis. Cognitive-behavioral therapy for psychosis can be effective. However, challenges in engagement and effectiveness remain.

Objective

To investigate the effects on paranoia and mechanisms of action of SlowMo, a digitally supported reasoning intervention, plus usual care compared with usual care only.

Design, setting, and participants

This parallel-arm, assessor-blinded, randomized clinical trial recruited participants at UK community health services from May 1, 2017, to May 14, 2019. Eligible participants consisted of a referral sample with schizophrenia-spectrum psychosis and distressing, persistent (≥3 months) paranoia.

Interventions

Individuals were randomized 1:1 to SlowMo, consisting of 8

SUBMITTER: Garety P 

PROVIDER: S-EPMC8027943 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature