Association of Loneliness and Wisdom With Gut Microbial Diversity and Composition: An Exploratory Study.

ABSTRACT: Loneliness and wisdom have opposite effects on health and well-being. Loneliness is a serious public health problem associated with increased morbidity and mortality. Wisdom is associated with better health and well-being. We have consistently found a strong negative correlation between loneliness and wisdom. The present study aimed to investigate the association of loneliness and wisdom with the gut microbiome. One hundred eighty-four community-dwelling adults (28-97 years) completed validated self-report-based measures of loneliness, wisdom, compassion, social support, and social engagement. Fecal samples were collected and profiled using 16S rRNA sequencing. Linear regression analyses, controlling for age and body mass index, revealed that lower levels of loneliness and higher levels of

SUBMITTER: Nguyen TT 

PROVIDER: S-EPMC8029068 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature