Vitamin C to pregnant smokers persistently improves infant airway function to 12 months of age: a randomised trial.

ABSTRACT:

Background

Vitamin C (500 mg·day^-1) supplementation for pregnant smokers has been reported to increase newborn pulmonary function and infant forced expiratory flows (FEFs) at 3 months of age. Its effect on airway function through 12 months of age has not been reported.

Objective

To assess whether vitamin C supplementation to pregnant smokers is associated with a sustained increased airway function in their infants through 12 months of age.

Methods

This is a pre-specified secondary outcome of a randomised, double-blind, placebo-controlled trial that randomised 251 pregnant smokers between 13 and 23 weeks of gestation: 125 to 500 mg·day^-1 vitamin C and 126 to placebo. Smoking cessation counselling was provided. FEFs performed at 3 and 12 months of

SUBMITTER: McEvoy CT 

PROVIDER: S-EPMC8029653 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature