Association between plasma retinol levels and the risk of all-cause mortality in general hypertensive patients: A nested case-control study.

ABSTRACT: To evaluate the association between plasma retinol levels with all-cause mortality and investigate the possible effect modifiers in general hypertensive patients with no previous cardiovascular disease (CVD). This case-control study was nested in the China Stroke Primary Prevention Trial (CSPPT), a randomized, double-blind, controlled trial conducted in 32 communities in Anhui and Jiangsu provinces in China. The current study included 617 cases of all-cause mortality and 617 controls matched on age (≤1 year), sex, treatment group, and study site. All-cause mortality was the main outcome in this analysis, which included death due to any reason. The median follow-up duration was 4.5 years. Overall, there was a U-shaped relation of plasma retinol with all-cause mortality. In the threshold eff

SUBMITTER: Li H 

PROVIDER: S-EPMC8030112 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature