Stage I hypertension is associated with impaired systolic function by strain imaging compared with prehypertension: A report from the prever study.

ABSTRACT: High blood pressure (BP) is associated with higher rates of cardiovascular events, even in stage I hypertension (HTN) and prehypertension (preHTN). Lower left ventricular (LV) systolic function, assessed by global longitudinal strain (GLS), has been demonstrated in individuals with HTN compared to individuals with normal BP, but a comparison of individuals with preHTN and stage I HTN was not described to date. The PREVER study includes two randomized double-blind controlled trials, performed in volunteers with preHTN (PREVER-prevention trial) or stage I HTN (PREVER-treatment trial), aged 30-70 years. A subsample of patients of both trials had GLS measured from 2D echocardiograms performed at baseline and after 18 months of follow-up. We compared baseline data from both studies and, among s

SUBMITTER: Santos ABS 

PROVIDER: S-EPMC8030492 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature