Personalized Profiling Reveals Donor- and Lactation-Specific Trends in the Human Milk Proteome and Peptidome.

ABSTRACT:

Background

Human milk is the most genuine form of personalized nutrition, whereby its nutritional and bioactive constituents support the changing needs of the growing infant. Personalized proteome profiling strategies may provide insights into maternal-infant relationships. Proteins and endogenous peptides in human milk play an important role as nutrients for growth and have distinct functionality such as immune defense. Comprehensive monitoring of all of the human milk proteinaceous components, including endogenous peptides, is required to fully understand the changing role of the human milk proteome throughout lactation.

Objective

We aimed to investigate the personalized nature of the human milk proteome and peptidome for individual mother-infant dyads.

Methods

Two

SUBMITTER: Zhu J 

PROVIDER: S-EPMC8030701 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature